Screening sperm may help identify potentially harmful new genetic mutations and help fertility specialists prevent them from being passed on to offspring, shows a preliminary study published in eLife. The results suggest a potential tool to help improve fertility treatment outcomes. New harmful disease-causing mutations can arise in sperm, and fathers may inadvertently pass them
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In a recent study posted to the medRxiv* pre-print server, researchers developed a mechanistic mathematical model to predict the course of vaccine-induced immunity in healthy and immunosuppressed patients for the long term, exceeding the time frames for which clinical data is currently available. Study: Mechanistic model for booster doses effectiveness in healthy, cancer and immunosuppressed
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In a recent study published in the bioRxiv* preprint server, researchers at the Medical University of Innsbruck assessed the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CLpro mutations responsible for Paxlovid resistance. The 3-chymotrypsin-like protease (3CLPro), or main protease (Mpro), is the main protease found in coronaviruses. Study: SARS-CoV-2 3CLpro mutations confer resistance to Paxlovid (nirmatrelvir/ritonavir) in
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The monkeypox virus is evolving 6-12 times faster than would be expected, according to a new study. The virus is thought to have a single origin, the genetic data suggests, and is a likely descendant of the strain involved in the 2017-2018 monkeypox outbreak in Nigeria. It’s not clear if these mutations have aided the
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South Korean health officials recently approved the use of the country’s first domestically developed COVID-19 vaccine, meant for people 18 years and older. The outcome of a public-private partnership, the vaccine was manufactured by the vaccine developer alongside the government, research institutes, and private experts. According to South Korea’s Food and Drug Safety Ministry officials during a briefing last week,
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Not all electronic cigarette devices are created equal. Some fourth-generation models – such as Juul devices – are associated with unique changes in markers of immune responses inside our airways, according to a new peer-reviewed paper from UNC School of Medicine researchers led by toxicologist Ilona Jaspers, PhD, director of the UNC Center for Environmental
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There’s been an explosion of environmentally friendly, cost-effective products for menstrual bleeding in recent years. Period underwear and menstrual cups in particular have gone from products few people were familiar with to household names. Each one has its benefits and drawbacks, and everyone who has a period has their own opinions on what’s the most
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A recent study published in JAMA Network Open found that women residing in socioeconomically disadvantaged neighborhoods in the United States (US) have moderately lower chances for conception without fertility treatment. Study: Association Between Neighborhood Disadvantage and Fertility Among Pregnancy Planners in the US. Image Credit: Chinnapong/Shutterstock Background Infertility imposes a tremendous economic burden in the US and
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Women with Diabetes – Benefits and Barriers to Exercise – Diabetes Daily Learning Center Learning Center: LearningCenter Diabetes Daily does not provide medical advice,diagnosis or treatment.Get additional information.© 2005 – 2022 Everyday Health, Inc. Everyday Health is among the federally registered trademarks of Everyday Health, Inc. and may not be used by third parties without
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More women entering general surgery careers is a harbinger of the medical workforce. The number of women in general surgery residency programs accredited by the Accreditation Council for Graduate Medical Education (ACGME) is rapidly approaching parity with the number of men. While this is an encouraging trend, gender equity is much more than numbers. Our
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The bacillus Calmette-Guérin (BCG) vaccine nearly halved the risk of progression among patients with non–muscle invasive bladder cancer (NMIBC) compared with transurethral resection of the bladder (TUR), but only among those with very high-risk disease. The study compared BCG to TUR with or without chemotherapy with regard to disease progression. BCG had no significant effect
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Asthmatic people may soon receive more effective treatments that would make breathing easier for them, thanks to a new study conducted by the Edith Cowan University (ECU) and Karolinska Institute.  With the research findings published in the European Respiratory Journal, the study, led by Dr. Stacy Reinke of ECU and Dr. Craig Wheelock of Karolinska Institute, found that severe
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As we head into summer, the rise in humidity and temperature creates an ideal environment for ticks to thrive in.1 In fact, warmer weather is associated with an increased risk of infections caused by ticks, specifically Lyme disease, Rocky Mountain spotted fever, and tick-borne encephalitis.1 As a result, it is important to learn about how
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In a recent study published in The Lancet, researchers in the United Kingdom determined whether an individual with a higher body mass index (BMI) mounted a weaker immune response to a coronavirus disease 2019 (COVID-19) vaccine. Additionally, they investigated vaccine uptake and the risk of severe COVID-19 outcomes in such individuals. Study: Associations of BMI
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In a recent article posted to the medRxiv* preprint server, researchers in the United States analyzed the pneumococcal carriage in older adults in the Greater New Haven Area, United States (US), during the implementation of coronavirus disease 2019 (COVID-19) mitigation strategies. Study: Persistence of pneumococcal carriage among older adults in the community despite COVID-19 mitigation measures.
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A new report, independently commissioned by the Secretary of State for Health and Social Care of the U.K., provides cutting-edge recommendations with the aim of achieving a “Smokefree 2030.” This reflects the U.K. government’s ambition to reduce the smoking rate from 13.5% to 5% by the end of this decade. Authored by Javed Khan OBE,
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A person’s estimated glomerular filtration rate (eGFR), a mainstay for assessing renal function and health, can often substantially differ from that person’s actual, directly measured GFR (mGFR), a test performed far less often but which may now warrant a wider role as new evidence documents just how divergent mGFR and eGFR can be. Tariq Shafi,
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The latest monkeypox outbreak update revealed that a small number of cases comprised kids and non-sexial contacts.  According to Dr. Hans Kluge, a small number of confirmed monkeypox cases among household members accounted for non-sexual contacts and children. In the update released Friday, the World Health Organization (WHO) regional director for Europe urged everyone to increase their efforts in
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