Clinical Trials & Research

GAITHERSBURG, Md., May 10, 2021 /PRNewswire/ – Novavax, Inc. (Nasdaq: NVAX), a biotechnology company developing next-generation vaccines for serious infectious diseases, today announced data from a preclinical study of the company’s combination quadrivalent seasonal flu vaccine (NanoFlu™) and COVID-19 vaccine candidate (NVX-CoV2373). The NanoFlu/NVX-CoV2373 combination vaccine demonstrated positive immune responses to both influenza and SARS-CoV-2. A pre-print of the
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May 10, 2021 — Today, the U.S. Food and Drug Administration expanded the emergency use authorization (EUA) for the Pfizer-BioNTech COVID-19 Vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to include adolescents 12 through 15 years of age. The FDA amended the EUA originally issued
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TOKYO & MUNICH & BASKING RIDGE, N.J.–(BUSINESS WIRE) May 08, 2021 –New data from Daiichi Sankyo Company, Limited (hereafter, Daiichi Sankyo) and AstraZeneca’s datopotamab deruxtecan (Dato-DXd), a TROP2 directed DXd antibody drug conjugate (ADC), showed preliminary response and disease control in patients with metastatic triple negative breast cancer (TNBC) with disease progression following standard treatment.
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A study presented at this year’s European Congress on Obesity (held online, 10-13 May) supports recommendations to avoid pregnancy for 12 months after bariatric (obesity) surgery due to an association with adverse outcomes in pregnancy including an elevated risk of preterm birth. The study is by Dr Laura Heusschen, Vitalys Obesity Clinic, part of Rijnstate
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Countries like the UK, Israel, and the USA are now in the thick of successful vaccine campaigns against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID-19 pandemic. As the vaccine rollout continues, there have been thousands of anecdotal reports of receivers suffering symptoms of mild fatigue, achiness, and fever in
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Follow-up of vaccinated and unvaccinated individuals at St. Jude Children’s Research Hospital, USA, revealed asymptomatic infection reduced by 90% and symptomatic infections reduced by up to 96% in vaccinated people compared to those not vaccinated. The Pfizer/BioNTech mRNA was approved for use in the USA in December 2020. Clinical trials reported an efficacy of 94.8%,
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Both vonoprazan-based treatment regimens demonstrated superior eradication rates vs. a standard of care proton pump inhibitor (PPI)-based triple therapy New Drug Application (NDA) submissions targeted for Q4 2021 FLORHAM PARK, N.J., April 29, 2021 (GLOBE NEWSWIRE) — Phathom Pharmaceuticals, Inc. (Nasdaq: PHAT), a late clinical-stage biopharmaceutical company focused on developing and commercializing novel treatments for
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St. Jude Children’s Research Hospital scientists have developed an integrated, high-throughput system to better understand and possibly manipulate gene expression for treatment of disorders such as sickle cell disease and beta thalassemia. The research appears today in the journal Nature Genetics. Researchers used the system to identify dozens of DNA regulatory elements that act together
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PREVENT-19 clinical trial expanded to assess the efficacy, safety and immunogenicity of NVX-CoV2373 for the prevention of COVID-19 in up to 3,000 12-17-year-old adolescents President of Research and Development, Gregory Glenn, M.D., to provide update regarding the additional trial arm during World Vaccine Congress GAITHERSBURG, Md., May 3, 2021 /PRNewswire/ — Novavax, Inc. (Nasdaq: NVAX),
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A team of scientists in Australia has recently investigated the health condition of Australian citizens who lost jobs during the coronavirus disease 2019 (COVID-19) pandemic. The study findings reveal that job loss is associated with a deterioration in mental health but an improvement in physical health. Importantly, retaining employment has shown a positive impact on
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May 6 2021 A global conference on human fertility has been warned of huge societal and ethical challenges regulating advances in gene editing in assisted reproduction. Speaking at the 10th Congress of the Asian Pacific Initiative of Reproduction (ASPIRE), Dr Catherine Racowsky said embryo gene editing was a growing likelihood among latest advances in IVF
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Publication of initial primary analysis highlights NVX-CoV2373 cross-protection against B.1.351 variant prevalent in South Africa during study GAITHERSBURG, Md., May 5, 2021 /PRNewswire/ — Novavax, Inc. (Nasdaq: NVAX), a biotechnology company developing next-generation vaccines for serious infectious diseases, today announced the publication of results from the initial primary analysis of a Phase 2b clinical trial
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Thought LeadersDr. Samantha WalkerDirector of Research & InnovationAsthma UK and the British Lung Foundation In light of World Asthma Day, News-Medical interviewed Dr. Samantha Walker from Asthma UK and the British Lung Foundation about some of the common misconceptions surrounding asthma. Please could you introduce yourself and tell us about your expertise in asthma? My
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Does a high dose of vitamin D reduce the number of days spent in hospital by patients with moderate to severe COVID-19? As previous studies have indicated, vitamin D can improve an individual’s immune response and insufficiencies of the vitamin could be a potential risk factor for respiratory tract infections. High serum levels of 25-hydroxyvitamin
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Social media may make it easier for people to engage online, but it does not provide certain benefits of real-life human interactions, says a Michigan State University researcher. Problematic social media use has been associated with depression, anxiety and social isolation, and having a good social support system helps insulate people from negative mental health.
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Vaccine candidate demonstrates high efficacy at 77% in a study of children aged 5-17 months conducted in Africa Novavax’ Matrix-M™ adjuvant used in combination with University of Oxford malaria vaccine candidate, R21, and developed in collaboration with Serum Institute of India Phase 3 clinical trial to evaluate safety and efficacy begun in 4,800 participants aged
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THOUSAND OAKS, Calif., April 28, 2021 /PRNewswire/ — Amgen (NASDAQ:AMGN) today announced that it agreed last night with the FDA’s proposed post-marketing requirement to conduct, as part of the ongoing development program, a multi-center randomized clinical trial to compare the safety and efficacy of Lumakras™ at 960 mg once daily versus a lower daily dose
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Scientists have known for a while that SARS-CoV-2’s distinctive “spike” proteins help the virus infect its host by latching on to healthy cells. Now, a major new study shows that they also play a key role in the disease itself. The paper, published on April 30, 2021, in Circulation Research, also shows conclusively that COVID-19
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CAMBRIDGE, Mass.–(BUSINESS WIRE)–Apr. 30, 2021– Moderna, Inc. (Nasdaq: MRNA), a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, today announced that the World Health Organization (WHO) has issued Emergency Use Listing (EUL) for its COVID-19 vaccine to prevent COVID-19 in individuals 18 years of age and older. “We thank the WHO for their data review and for their issuance of
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