Clinical Trials & Research

Data from a nationally representative survey indicate that in 2019, nearly three-fourths of U.S. adults reporting buprenorphine use did not misuse the medication in the past 12 months. In addition, buprenorphine misuse among people with opioid use disorder trended downward between 2015-2019, despite increases in the number of people receiving buprenorphine treatment. The study, published

As part of its commitment to enhance access to high-quality care, NYU Langone Health has opened NYU Langone Ambulatory Care Bethpage—one of Nassau County’s largest multispecialty care centers—at 185 Central Avenue. “Our presence on Long Island continues to grow with the opening of an expansive care center in Bethpage,” says Andrew Rubin, senior vice president

Counties that banned in-person religious gatherings and those with a greater number of hospitals per capita were associated with a decreased case-fatality rate of COVID-19 during the pandemic’s first wave, according to a new University of Michigan study. On the other hand, counties with high prevalence of asthma and a greater concentration of people over

A devastating genetic disease called CDKL5 deficiency disorder (CDD), which strikes in early childhood, may be significantly treatable even in adulthood, a new study from the Perelman School of Medicine at the University of Pennsylvania suggests. CDD is caused by the mutation of a gene called CDKL5, which is thought to play an important role

A new study investigates whether there is an association between cannabis and heart attacks in young adults. Cannabis is becoming legalized in a growing number of places, both for recreational and medical use.  Its use is also relatively common; one 2019 Gallup poll found that 12 percent of U.S. adults reported smoking cannabis.1 Young adults

A study led by the University of Birmingham has revealed for the first time that the contraceptive pill can reduce the risk of type 2 diabetes by over a quarter in women with polycystic ovary syndrome (PCOS). The research findings also show that women with PCOS have twice the risk of developing type 2 diabetes

Mapping of the complete genome of the obesity-prone Ossabaw pig gives new hope for further insights into human obesity and associated diseases. For the first time in history, researchers at DTU Bioengineering and DTU Health Tech in collaboration with researchers in China and the US have mapped the complete genome of the exceptional Ossabaw pig.

A recent study, published in the preprint server, medRxiv*, analyzes real-world data using artificial intelligence to provide insights into using ondansetron, an antiemetic agent, among severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive patients. Study: Ondansetron use is associated with lower COVID-19 mortality in a Real-World Data network-based analysis. Image Credit: Sonis Photography/ Shutterstock SARS-CoV-2

The National Institutes of Health is funding bold, new research ideas that focus on interventions to address health disparities and advance health equity. Eleven grants were awarded to support the work of exceptionally creative researchers across the United States through the NIH Common Fund’s Transformative Research to Address Health Disparities and Advance Health Equity initiative

A recent study published in the journal Viruses identifies a novel Alphacoronavirus (HCQD-2020) isolated from bats, in Korea, in 2020. They found that the amino acid sequence of a putative ORF7 at the 3’ terminator of HCQD-2020’s genome was not homologous with any of the known protein sequences, making it the most likely distinct ORF

Measuring the weight of the fetus is an important part of keeping both mother and baby safe, since a clinically high birth weight is a risk factor for pregnancy-related complications. A recent study investigated 3D limb volume together with abdominal circumference to create a measurement that would be able to predict fetal weight. According to

Linkam Scientific Instruments, expert in sample characterisation, has launched a new Water Circulation Pump (WCP), designed specifically to provide optimised water cooling to its range of temperature and environmental control stages. When used with Linkam’s Peltier stages, the WCP is able to hold sample temperatures as low as -30°C (with an ambient temperature of 21°C).

Children are not at risk for more severe COVID-19 disease with Delta compared to earlier severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, finds a new medRxiv* preprint study. In the first large-scale epidemiological study comparing SARS-CoV-2 infection between variants in children, researchers found children were more likely to be as sick from Delta as

EKF Diagnostics Holdings plc (AIM: EKF), the AIM-listed point-of-care business, announces that it has agreed to acquire, pursuant to the terms of a securities purchase agreement dated 27 September 2021 (“SPA”), the entire issued capital of Advanced Diagnostic Laboratory LLC (“ADL Health”), a Texas based PCR-focused testing laboratory certified under the Clinical Laboratory Improvement Amendments (“CLIA”)

The spike (S) protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the virus responsible for the coronavirus disease 2019 (COVID-19), consists of two subunits including the S1 and S2 subunits. The S1 bears the receptor-binding domain (RBD), which is responsible for the interaction of the virus with the angiotensin-converting enzyme 2

A digital program enhancing physical and mental wellbeing for young people adjusting to life after cancer, will be developed by The University of Queensland in partnership with cancer support organisation Canteen. The project BALANCE has been awarded $1.37 million from the National Health and Medical Research Council. Project leader Professor Sandie McCarthy, from UQ’s School

Cases of major depressive disorder and anxiety disorders have increased by more than 25 per cent worldwide, according to a world-first study of the impact of COVID-19 on mental health. The research, led by researchers from The University of Queensland’s School of Public Health, Queensland Centre for Mental Health Research and Institute for Health Metrics

During the pandemic, it has become increasingly evident that people with cardiovascular disease and obesity are at a much higher risk of developing very severe, even fatal COVID-19 disease. Researchers at Karolinska Institutet in Sweden have identified some metabolic processes that SARS-CoV-2 uses to attack lung tissue. The results, which are published in Molecular &

A new preprint deals with the characterization of neutrophil phenotypes in an attempt to provide biomarkers that can predict severe disease in patients hospitalized with coronavirus disease 2019 (COVID-19). Study: Longitudinal characterization of circulating neutrophils uncovers distinct phenotypes associated with disease severity in hospitalized COVID-19 patients. Image Credit: Kateryna Kon/ Shutterstock A preprint version of

Coronavirus disease 2019 (COVID-19) caused worldwide health and economic crises. While the development and mass administration of vaccines has successfully halted the progression of the disease in some countries, many are still struggling with the disease burden. Study: Clinical utility of Elecsys Anti-SARS-CoV-2 S assay in COVID-19 vaccination: An exploratory analysis of the mRNA-1273 phase

In one of the largest and most racially diverse studies to date of American children and adolescents with type 1 and type 2 diabetes, researchers at Johns Hopkins Medicine, Baylor College of Medicine and the University of Wisconsin have identified the clinical and demographic factors associated with pediatric diabetic retinopathy. The disorder, a leading cause

A modeling analysis has demonstrated effective management of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant outbreaks in Australia by adopting a strategy that includes implementing an achievable 80% vaccine coverage in ages five-plus with moderate physical distancing measures. Study: Non-pharmaceutical interventions and vaccinating school children required to contain SARS-CoV-2 Delta variant outbreaks

The current coronavirus disease 2019 (COVID-19) pandemic has caused severe and wide-ranging changes in behavior due to the implementation of various non-pharmaceutical interventions (NPIs) in order to contain the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A new study published on the preprint server medRxiv* discusses dietary changes as a result of

Researchers from Israel have described a new molecular assay to rapidly detect pathogens with high sensitivity in clinical samples. The method combines a highly sensitive magnetic modulation biosensing (MMB) system, rapid thermal cycling, and a modified double-quenched hydrolysis probe to detect the presence of RNA. Study: A magnetic modulation biosensing-based molecular assay for rapid and

People with rapid eye movement (REM) sleep behavior disorder act out their dreams. While sleeping safely in bed, for example, they might throw up their arms to catch an imaginary ball, or try to run from an illusory assailant. Such actions are more than just a nuisance. People with the disorder have a 50 to

If you are someone with asthma, you may have noticed that your breathing problems get worse during the night. After all, nearly 75% of people with asthma claim that they experience more harsh symptoms at night.1 This issue is something that researchers at the Brigham & Women’s Hospital and Oregon Health & Science University have

Coronavirus disease 2019 (COVID-19) modelling has shown itself to be drastically important to public health policy. With millions of deaths and hundreds of millions of cases worldwide, knowing the likely spread and risk of the disease helped governments apply lockdowns, social distancing measures, and other restrictions to minimize the spread of the disease and buy