Clinical Trials & Research

May 11 2021 BioEcho Life Sciences announces that the company has recently received CE-mark approval for their EchoLUTION Viral RNA/DNA Swab Kit product line, which has been classified as a medical device Class A IVD in the European Union. To obtain this certification the products have to comply with the regulation 2017/746 of the European

GAITHERSBURG, Md., May 10, 2021 /PRNewswire/ – Novavax, Inc. (Nasdaq: NVAX), a biotechnology company developing next-generation vaccines for serious infectious diseases, today announced data from a preclinical study of the company’s combination quadrivalent seasonal flu vaccine (NanoFlu™) and COVID-19 vaccine candidate (NVX-CoV2373). The NanoFlu/NVX-CoV2373 combination vaccine demonstrated positive immune responses to both influenza and SARS-CoV-2. A pre-print of the

May 10, 2021 — Today, the U.S. Food and Drug Administration expanded the emergency use authorization (EUA) for the Pfizer-BioNTech COVID-19 Vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to include adolescents 12 through 15 years of age. The FDA amended the EUA originally issued

Cerebral aneurysms are malformations caused by abnormalities on the walls of blood vessels in the brain. When these blood vessels rupture, about 30% of the sufferers die on the spot, giving these the rightful label of ‘ticking bombs in the head’. Recently, a research team at POSTECH has come up with a new treatment that

TOKYO & MUNICH & BASKING RIDGE, N.J.–(BUSINESS WIRE) May 08, 2021 –New data from Daiichi Sankyo Company, Limited (hereafter, Daiichi Sankyo) and AstraZeneca’s datopotamab deruxtecan (Dato-DXd), a TROP2 directed DXd antibody drug conjugate (ADC), showed preliminary response and disease control in patients with metastatic triple negative breast cancer (TNBC) with disease progression following standard treatment.

Kai Humphrey, 9, has been learning from home for more than a year. He badly misses his Washington, D.C., elementary school, along with his friends and the bustle of the classroom. “I will be the first person ever to have every single person in the world as my friend,” he said on a recent Zoom

A study presented at this year’s European Congress on Obesity (held online, 10-13 May) supports recommendations to avoid pregnancy for 12 months after bariatric (obesity) surgery due to an association with adverse outcomes in pregnancy including an elevated risk of preterm birth. The study is by Dr Laura Heusschen, Vitalys Obesity Clinic, part of Rijnstate

Spurred by unproven assumptions that vaping is safer than smoking cigarettes, a team at West Virginia University is conducting a three-year study on the effects of vaping during pregnancy. It is estimated that half of all women who smoke prior to becoming pregnant will continue to smoke during and after the pregnancy. The impact of

A comprehensive review into what we know about COVID-19 and the way it functions suggests the virus has a unique infectious profile, which explains why it can be so hard to treat and why some people experience so-called “long-COVID”, struggling with significant health issues months after infection. There is growing evidence that the virus infects

Countries like the UK, Israel, and the USA are now in the thick of successful vaccine campaigns against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID-19 pandemic. As the vaccine rollout continues, there have been thousands of anecdotal reports of receivers suffering symptoms of mild fatigue, achiness, and fever in

Follow-up of vaccinated and unvaccinated individuals at St. Jude Children’s Research Hospital, USA, revealed asymptomatic infection reduced by 90% and symptomatic infections reduced by up to 96% in vaccinated people compared to those not vaccinated. The Pfizer/BioNTech mRNA was approved for use in the USA in December 2020. Clinical trials reported an efficacy of 94.8%,

Both vonoprazan-based treatment regimens demonstrated superior eradication rates vs. a standard of care proton pump inhibitor (PPI)-based triple therapy New Drug Application (NDA) submissions targeted for Q4 2021 FLORHAM PARK, N.J., April 29, 2021 (GLOBE NEWSWIRE) — Phathom Pharmaceuticals, Inc. (Nasdaq: PHAT), a late clinical-stage biopharmaceutical company focused on developing and commercializing novel treatments for

St. Jude Children’s Research Hospital scientists have developed an integrated, high-throughput system to better understand and possibly manipulate gene expression for treatment of disorders such as sickle cell disease and beta thalassemia. The research appears today in the journal Nature Genetics. Researchers used the system to identify dozens of DNA regulatory elements that act together

PREVENT-19 clinical trial expanded to assess the efficacy, safety and immunogenicity of NVX-CoV2373 for the prevention of COVID-19 in up to 3,000 12-17-year-old adolescents President of Research and Development, Gregory Glenn, M.D., to provide update regarding the additional trial arm during World Vaccine Congress GAITHERSBURG, Md., May 3, 2021 /PRNewswire/ — Novavax, Inc. (Nasdaq: NVAX),

A team of scientists in Australia has recently investigated the health condition of Australian citizens who lost jobs during the coronavirus disease 2019 (COVID-19) pandemic. The study findings reveal that job loss is associated with a deterioration in mental health but an improvement in physical health. Importantly, retaining employment has shown a positive impact on

A research group from the Johns Hopkins University School of Medicine has published a new study that suggests certain COVID-19 vaccines may protect against variant coronavirus strains.1 These include the variants first identified in the U.K. and South Africa. The study analyzed the response of the SARS-CoV-2 virus and three other common cold coronaviruses after

May 6 2021 A global conference on human fertility has been warned of huge societal and ethical challenges regulating advances in gene editing in assisted reproduction. Speaking at the 10th Congress of the Asian Pacific Initiative of Reproduction (ASPIRE), Dr Catherine Racowsky said embryo gene editing was a growing likelihood among latest advances in IVF

Publication of initial primary analysis highlights NVX-CoV2373 cross-protection against B.1.351 variant prevalent in South Africa during study GAITHERSBURG, Md., May 5, 2021 /PRNewswire/ — Novavax, Inc. (Nasdaq: NVAX), a biotechnology company developing next-generation vaccines for serious infectious diseases, today announced the publication of results from the initial primary analysis of a Phase 2b clinical trial

People who clock six to seven hours of sleep a night had the lowest chance of dying from a heart attack or stroke when compared with those who got less or more sleep, according to a study being presented at the American College of Cardiology’s 70th Annual Scientific Session. This trend remained true even after

Thought LeadersDr. Samantha WalkerDirector of Research & InnovationAsthma UK and the British Lung Foundation In light of World Asthma Day, News-Medical interviewed Dr. Samantha Walker from Asthma UK and the British Lung Foundation about some of the common misconceptions surrounding asthma. Please could you introduce yourself and tell us about your expertise in asthma? My

Does a high dose of vitamin D reduce the number of days spent in hospital by patients with moderate to severe COVID-19? As previous studies have indicated, vitamin D can improve an individual’s immune response and insufficiencies of the vitamin could be a potential risk factor for respiratory tract infections. High serum levels of 25-hydroxyvitamin

If you come from a family where people routinely live well into old age, you will likely have better cognitive function (the ability to clearly think, learn and remember) than peers from families where people die younger. Researchers affiliated with the Long Life Family Study (LLFS) recently broadened that finding in a paper published in

Social media may make it easier for people to engage online, but it does not provide certain benefits of real-life human interactions, says a Michigan State University researcher. Problematic social media use has been associated with depression, anxiety and social isolation, and having a good social support system helps insulate people from negative mental health.

Vaccine candidate demonstrates high efficacy at 77% in a study of children aged 5-17 months conducted in Africa Novavax’ Matrix-M™ adjuvant used in combination with University of Oxford malaria vaccine candidate, R21, and developed in collaboration with Serum Institute of India Phase 3 clinical trial to evaluate safety and efficacy begun in 4,800 participants aged

New research shows that patients who have had contact with the hospital due to serious glandular disease have a greater risk of subsequently developing depression. The study from iPSYCH is the largest yet to show a correlation between glandular fever and depression. The vast majority of Danes have had glandular fever – also called mononucleosis

THOUSAND OAKS, Calif., April 28, 2021 /PRNewswire/ — Amgen (NASDAQ:AMGN) today announced that it agreed last night with the FDA’s proposed post-marketing requirement to conduct, as part of the ongoing development program, a multi-center randomized clinical trial to compare the safety and efficacy of Lumakras™ at 960 mg once daily versus a lower daily dose

Scientists have known for a while that SARS-CoV-2’s distinctive “spike” proteins help the virus infect its host by latching on to healthy cells. Now, a major new study shows that they also play a key role in the disease itself. The paper, published on April 30, 2021, in Circulation Research, also shows conclusively that COVID-19

CAMBRIDGE, Mass.–(BUSINESS WIRE)–Apr. 30, 2021– Moderna, Inc. (Nasdaq: MRNA), a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, today announced that the World Health Organization (WHO) has issued Emergency Use Listing (EUL) for its COVID-19 vaccine to prevent COVID-19 in individuals 18 years of age and older. “We thank the WHO for their data review and for their issuance of