Clinical Trials & Research

A recent study investigated the effects of vaping on lung cells. The debate surrounding the negative health effects of e-cigarettes is becoming ever more polarised. Scientists at the new University North Caroline School of Medicine, led by Rob Tarran, have recently carried out a study examining the effects of ‘’vaping’’ on the cellular responses within
0 Comments
A recent study on over 7 million medical records found a dose-dependent correlation between statins and osteoporosis diagnosis. Statins are a class of cholesterol-lowering medications prescribed to reduce the risk of cardiovascular disorders. Statins act by inhibiting HMG-CoA reductase, which is the main enzyme involved in cholesterol biosynthesis, thus effectively lowering LDL cholesterol in blood
0 Comments
Researchers examine oral microbiota and its possible link to child and adolescent obesity. Worldwide, obesity remains a major health issue, with rates of obesity on the rise in both adults and children. Obesity can be influenced by genetics; however, environmental, social, and psychological factors play a large role. Previous research has shown distinctions in taste
0 Comments
Newly discovered activity of the leukemia drug, nilotinib, shows promise for being useful to treat certain types of cancer. Hedgehog-dependent medulloblastoma is a deadly brain cancer that makes up about one-third of all childhood brain cancers. The Hedgehog (Hh) molecular signaling pathway and its specific component, Smoothened (SMO), is important for normal embryonic development. Abnormal
0 Comments
Researchers in the UK conducted a comparative study on the outcome of surgery & non-surgical treatment for varicose veins. The study (aptly named CLASS – Comparison of Laser, Surgery and Foam Sclerotherapy) was a large, multi-center randomized trial conducted across 11 centers in the UK. It involved two non-surgical treatments, Foam Sclerotherapy and Laser Ablation,
0 Comments
Dapagliflozin, a drug originally developed to treat diabetes, shows benefit in patients in heart failure. Dapagliflozin belongs to a relatively new class of drugs, the sodium-glucose co-transporter-2 inhibitors, for treating type 2 diabetes mellitus. This new class of drugs reduces blood glucose levels by reducing the reabsorption of glucose in the kidneys. Clinical trials treating
0 Comments
Sertraline, an antidepressant that doctors commonly prescribe, appears to work by reducing anxiety first and doesn’t start tackling depressive symptoms until weeks later. New research sheds fresh light on how antidepressants work. This was the main finding of a study on the use of antidepressants in primary care settings in the United Kingdom. The researchers
0 Comments
Study shows the benefit of resuming blood thinner drugs after a gastrointestinal bleed outweighs the risk of a rebleeding event. Gastrointestinal (GI) bleeding is a common problem affecting approximately 150 patients per 100,000 population in the United States and the United Kingdom and has a mortality rate of 5% to 10%. GI bleeding can be
0 Comments
Researchers have demonstrated an association between diet-mediated remission in inflammatory bowel disease and microbiome composition. Inflammatory bowel disease (IBD) is an umbrella name for various gastrointestinal tract disorders, the most abundant is Crohn’s disease in humans. Years of research have suggested that a combination of environmental factors and genetic susceptibility plays a role in the
0 Comments
Biting down on an oral orthotic device may suppress tics in patients with Tourette Syndrome. Tourette Syndrome is a neurological disorder characterized by repetitive and involuntary movements or sounds called tics. Simple motor tics can present as eye movements, grimacing, herd jerks, or shoulder shrugs. Simple vocal tics include throat-clearing, coughing, sniffing, barking, and grunting
0 Comments
Medical treatment for addiction that targets the brain cells responsible for drug cravings may be the key to preventing relapse. In the United States alone, almost 20 million adults suffer from addiction to drugs or alcohol. Addiction is a chronic relapsing disorder and preventing relapse is one of the major goals of addiction treatment. Despite
0 Comments
A recent study investigated the effects of alternate day fasting, finding that participants had reduced total caloric intake and improved markers of cardiovascular health. A recent clinical trial demonstrated that alternate day fasting for a period of four weeks was able to improve markers of overall health, including markers of cardiovascular health, reduced fat mass,
0 Comments
A recent study investigated how the microbiome affects the critical growth period during infancy, specifically, how it might impact on the growth of preterm infants. Parents today are heavily educated by their own parents and the media controlled by the multi-billion-dollar parenting industry. As a new parent today, there are so many resources to ensure
0 Comments
A recent study, published in the British Medical Journal, investigated the association between dairy product intake and mortality. Consumption of dairy products, including milk and cheese, has been controversial in terms of health effects, leaving consumers confused as to whether their favourite dairy products are good or bad for their health. As part of the
0 Comments
A new study looks at how feeding and the desire to eat is regulated by stress-related emotional responses. Eating is a behaviour that is strongly influenced by stress-related emotional responses. Emotional states, in response to potential environmental dangers, compete with the desire to eat thus making eating a complex behaviour. Temporary changes to eating habits
0 Comments
Researchers have successfully tested a new treatment for drug-resistant acute lymphoblastic leukemia on a new mouse model. Acute lymphoblastic leukemia is the most common cancer in children and accounts for about 20% of adult leukemias. Even though there are a number of therapies that improve survival rates, some patients still experience recurrence of the disease
0 Comments
Scientists investigate whether diet can help prevent fatigue in multiple sclerosis patients. Multiple sclerosis (MS) is an autoimmune disorder that affects the brain and spinal cord. The body’s immune system attacks the cells (oligodendrocytes) that make the fatty covers that surround nerve cells. This fatty cover is called the myelin sheath, this is why MS
0 Comments
Aronia berry extract positively affects indicators of cardiovascular health. In a recent study, researchers investigated the effects of Aronia berry supplements in healthy participants. Specifically, they wanted to test the effects of these supplements on vascular function and the composition of the gut microbiome. In this clinical trial, 66 healthy men were divided into three
0 Comments