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Boys born to mothers infected with SARS‐CoV‐2 during pregnancy may be more likely to receive a diagnosis of a neurodevelopmental disorder by age 12 months, according to new research. Andrea G. Edlow, MD, MSc, with Massachusetts General Hospital and Harvard Medical School in Boston, and colleagues examined data from 18,355 births between March 1, 2020,
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Jurassic Park actor Sam Neill was recently interviewed by The Guardian in advance of the release of his memoir, Did I Ever Tell You? Originally planned as a glimpse into his career, his life as a celebrity, and his farm in New Zealand, the book takes a dark turn in chapter 1: “The thing is,
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Though the first COVID-19 bivalent booster was not well-received when it launched last year, U.S. public health officials have started discussing rolling out another round of bivalent booster doses.  A source familiar with the deliberations told CNN on condition of anonymity this week that health authorities have already started to weigh whether the country should
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In the UNITE (Urothelial Cancer Network to Investigate Therapeutic Experiences) study, researchers looked at the experience with enfortumab vedotin (EV, Padcev) in patient subsets for which activity had not been well defined in clinical trials. At the recent Genitourinary Cancers Symposium, new findings on biomarkers of response in the trial were presented by Tanya Jindal,
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. A key player in the body’s ability to attack COVID-19 is weakened among people who were infected before getting their first two shots of mRNA vaccine, new research suggests. But even though the key cells (CD8+ T cells) were found to
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Perinatal care differs by race and ethnicity, with greater disparities in care for more stigmatizing conditions such as depression and substance use, according to a retrospective study. For example, compared with white women, Black women were less likely to receive a prenatal depression screen (OR 0.8, 95% CI 0.7-0.9) and more likely to be given
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Sports-related sudden cardiac arrest (Sr-SCA) appears to be extremely rare in women compared with men, despite similar characteristics and circumstances of occurrence, data from three European population-based registries suggest. “Our study shows that cardiac arrest during sports activities is up to 13 times less frequent in women, which means that the risk of sports-related cardiac
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Last week, Match applicants learned if they matched into a residency program. Posts celebrating the 2023 Match results flooded social media, with many expressing happiness and excitement about the future. This is because the Match is not just any other day — it culminates the medical school experience and confirms many students’ identity as future
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The US Drug Enforcement Administration (DEA) is warning the public about a sharp increase in trafficking in fentanyl mixed with the animal tranquilizer xylazine, stating that the agency has seized mixtures of the two drugs in 48 states. The DEA warning comes on the heels of a US Food and Drug Administration announcement that it
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For the heart failure population, BMI obesity no longer appeared to hold counterintuitive protective effects after comprehensive adjustment for natriuretic peptides and other prognostic variables in a post hoc analysis of PARADIGM. Eliminating this so-called “obesity paradox,” researchers found that study participants with the highest BMIs actually had excess combined heart failure hospitalizations and cardiovascular
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The study covered in this summary was published on researchsquare.com as a preprint and has not yet been peer reviewed. Key Takeaway Why This Matters Liver metastases are common among patients with NETs. Surgical debulking relieves symptoms and improves long-term survival. Parenchymal-sparing liver resection with microwave ablation is one surgical option, but reports on patient
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Tofersen, an investigational antisense drug developed to treat amyotrophic lateral sclerosis (ALS) associated with a mutation in the SOD1 gene (SOD1-ALS), may have clinical benefit, FDA reviewers indicated in briefing documents ahead of an advisory committee meeting. On Wednesday, the Peripheral and Central Nervous System Drugs Advisory Committee will vote on whether evidence supporting a
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Even relatively small changes in cardiorespiratory fitness (CRF) are associated with “considerable” impact on clinical symptoms and mortality risk among individuals with and without cardiovascular disease, new observational data in United States veterans suggest. “We had a few surprises,” Peter Kokkinos, PhD, Rutgers University, New Brunswick, New Jersey, and the VA Medical Center, Washington, DC,
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Revumenib, an investigational menin inhibitor, yielded encouraging responses in patients with relapsed or refractory KMT2A-rearranged or NPM1-mutant acute leukemia in the first-in-human test of the oral agent. In the phase 1 trial of 60 patients, more than half responded to revumenib, and 18 achieved complete or near-complete remission over a median of 9 months. Among
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NEW ORLEANS — Patients with severe alopecia areata had dramatic hair regrowth at 6 months with an investigational Janus kinase (JAK) inhibitor, according to a study reported here. Almost 40% of patients had at least 80% scalp coverage with the higher of two doses of the JAK 1/2 inhibitor deuruxolitinib (CTP-543), including 35% who had
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