Selpercatinib will expand treatment options available for people with RET fusion positive non small cell lung cancer. Non small cell lung cancer cells. The National Institute for Health and Care Excellence (NICE) has recommended the use of selpercatinib (Retevmo) for some people in England with a type of advanced non small cell lung cancer. The
cancer
Chemotherapy has a wide range of side effects, including fatigue, hair loss, and brain fog. Fast-growing cells throughout the body are targeted by this treatment, which can in turn damage digestive tract cells, as well. A new study says breast milk could be helpful in minimizing those digestive side effects. Researchers from Vanderbilt University had
In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow. The protein twosome, PADI4 and HIF-1, ramp up their activity under low-oxygen conditions that are typically
A known tumor suppressor gene plays role in stress protection of adult progenitor cells
A Utah businesswoman was diagnosed with breast cancer more than ten years ago, at the age of 37. Though she survived and remains cancer-free, the bills were overwhelming. A generous stranger helped her cover her expenses, and she decided to pay it forward with a fundraising effort. Swig’s “Save the Cups” initiative raises money for
When she was six months pregnant, Desiree Doughty noticed that something seemed to be wrong with her breasts. “I noticed that one of my breasts was bigger than the other,” she says. “I immediately became alert, because breast cancer runs in my family. My mother died of breast cancer at age 47.” Desiree, a preschool
In an exciting study published in Cell Metabolism, researchers uncover mechanisms that link cancer with metabolic and sleep disturbances. Patients with cancer often complain about sleep problem and metabolic disturbances. This is associated with reduced quality of life for patients with such problems. However, until recently the molecular basis for this phenomenon was not known.
Bits of DNA that were once considered useless actually contain instructions for making molecules that help cancer spread, say scientists. What scientists thought was ‘junk DNA’ actually helps cancer spread. The molecules in question are called enhancer RNAs (eRNAs), and a new study conducted by the University of California, San Diego (UCSD) revealed that they
A new form of radiotherapy may significantly improve survival for people with prostate cancer. A new clinical trial shows the benefits of an innovative form of radiation therapy, which delivers the radiation in only five sessions instead of the usual 37. The National Cancer Institute (NCI) estimate that prostate cancer affects over 160,000 people in
Despite medical science’s unbroken stream of discoveries, a number of high profile diseases still fox researchers. Today, scientists seek fresh clues along well-trodden paths. The cell: both tiny and vast. As scientists delve deeper into the mechanisms that lie beneath difficult-to-treat conditions such as diabetes and Alzheimer’s disease, they pick away at the edges of
Our Reader Score [Total: 8 Average: 3] A group of researchers around the world modified the existing endocrine therapy with ribociclib medications to treat breast cancer better. Breast cancer is the second leading cause of cancer death in Canadian women. About 1 in 4 Canadian women will develop breast cancer over the course of their
Researchers from many international institutions have teamed up to design a more effective drug for liver cancer therapy. Their compound may help improve survival rates and reduce adverse effects. International researchers develop a drug that they hope may come to improve liver cancer treatment. Hepatocellular carcinoma, or primary liver cancer, tends to grow and expand
Our Reader Score [Total: 0 Average: 0] A recent literature review published in The Lancet Oncology analyzed the probability of gastrointestinal cancer risk in cystic fibrosis patients. Cystic fibrosis is a genetic disease. It is caused by a change in the gene that forms a protein in the cell membranes called cystic fibrosis transmembrane conductance
A molecular discovery could explain why some cases of breast cancer do not respond to radiation therapy. It could also lead to additional treatments that improve the response in those cases. What could this new discovery do for breast cancer treatment? The results of the new study, which the Medical University of South Carolina in
Cancer cells function less well and are less able to multiply when their internal environment is made more acidic. Making cancer cells more acidic could quell their ability to multiply. This was the conclusion that researchers in the United States and Spain came to after they used a computer model to study the conditions that